SnapShot: Mitochondrial Architecture

SnapShot: Mitochondrial Architecture

Mammals C. elegans 1 TM domain; C-term in IMS and N-term in the matrix. IBM & CJ; self-oligomerizes, binds MICOS/MINOS/MitOS components and Sam50, Tob38, Ugo1, Fzo1. Yeast are viable but exhibit altered mtDNA inheritance and decreased respiratory growth. Mammals and worms exhibit increased ROS production and apoptosis. Loss of CJ, altered cristae structure, accumulation of cristae stacks and cr...

SnapShot: Mitochondrial Dynamics

SnapShot: Mitochondrial Quality Control

SnapShot: Import and Sortingof Mitochondrial Proteins

4.2 Mitochondrial Architecture and Heterogeneity

2 The Architecture of Neuronal Mitochondria . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 263 2.1 The Crista Junction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 264 2.2 Two Hypotheses . . . . . . . . . . . . . . . . . . ...